Suhasini has acted in Telugu, Tamil, Malayalam, Kannada, and movies. She began her career as a makeup artist for several major players in this period. In Kannada, played in several films such as bandhana and Muttina Haara (1990), headed by Rajendra Singh Babu, Benkiyalli Aralida Hoovu (1983), directed by K. Suprabhatha Balchander directed by Dinesh Babu. In Kannada films, it is a popular artist, especially in movies that were hits at the box office Vishnuvardhan. It was in Malayalam Cinema through Koodevide Padma Rajan (1983), which also introduced Mammootty. His role in the AFI nominated feature hard Vaanaprastham (1999), featuring Mohanlal, was particularly well received.
She won the National Film Award for Best Actress in 1986 for her role in Tamil film Sindhu Bhairavi 1985, directed by K. Balachander. In 1996 he entered the address with Indira Suhasini. She also wrote the screenplay for the film. The project was produced by G. V. films.
Suhasini Mani Ratnam and her husband are involved in the management of their production company Madras Talkies, with G. Srinivasan.
Most movies are in Telugu, Suhasini.
She has performed with famous actors like Krishna and Chiranjeevi. With Chiranjeevi, she appeared in over 20 films, the majority of blockbusters. His last appearance in a leading Telugu film was well received.